Anthony Martial and Wayne Rooney will both start in attack for Manchester United, while Axel Tuanzebe makes his league debut in Sunday's visit to Arsenal.
For Arsenal, Arsene Wenger goes with a back three with Rob Holding starting, and Aaron Ramsey and Granit Xhaka in the centre of midfield. Former United striker Danny Welbeck leads the Gunners' line.
See starting line up and subs below:
Arsenal: Cech; Holding, Koscielny, Monreal; Oxlade-Chamberlain, Ramsey, Xhaka, Gibbs; Ozil, Sanchez; Welbeck. Subs: Ospina, Gabriel, Bellerin, Coquelin, Iwobi, Walcott, Giroud.
Man Utd: De Gea; Tuanzebe, Smalling, Jones, Darmian; Carrick, Herrera; Mata, Mkhitaryan, Martial; Rooney. Subs: Romero, Pogba, Lingard, McTominay, Bailly, Blind, Rashford.
For Arsenal, Arsene Wenger goes with a back three with Rob Holding starting, and Aaron Ramsey and Granit Xhaka in the centre of midfield. Former United striker Danny Welbeck leads the Gunners' line.
See starting line up and subs below:
Arsenal: Cech; Holding, Koscielny, Monreal; Oxlade-Chamberlain, Ramsey, Xhaka, Gibbs; Ozil, Sanchez; Welbeck. Subs: Ospina, Gabriel, Bellerin, Coquelin, Iwobi, Walcott, Giroud.
Man Utd: De Gea; Tuanzebe, Smalling, Jones, Darmian; Carrick, Herrera; Mata, Mkhitaryan, Martial; Rooney. Subs: Romero, Pogba, Lingard, McTominay, Bailly, Blind, Rashford.